A macrophage-activating factor (MAF) is a lymphokine or other receptor based signal that primes macrophages towards cytotoxicity to tumors, cytokine secretion, or clearance of pathogens. Similar molecules may cause development of an inhibitory, regulatory phenotype. A MAF can also alter the ability of macrophages to present MHC I antigen, particip...
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http://en.wikipedia.org/wiki/Macrophage-activating_factor
An agent that stimulates macrophages to attack and ingest cancer cells. They are secreted by stimulated lymphocytes that prime macrophages to become non-specifically cytotoxic to tumours. ... They also modulate the expression of macrophage cell surface ia antigens. One maf is interferon-gamma (interferon type II). Other factors antigenically distin...
Found on
http://www.encyclo.co.uk/local/20973
(MAF) interferon-α.
Found on
http://www.encyclo.co.uk/local/21001
(MAF) Type: Term Definitions: 1. a primarily CD4+ T-cell-derived lymphokine that induces macrophage activation. The major macrophage-activating factor is interferon gamma. In the mouse, interleukin-4 is also an MAF.
Found on
http://www.medilexicon.com/medicaldictionary.php?t=31726
No exact match found.
